Serum levels of caspase-cleaved cytokeratin-18 in patients with severe traumatic brain injury are associated with mortality: a pilot study.

Serum levels of caspase-cleaved cytokeratin-18 in patients with severe traumatic brain injury are associated with mortality: a pilot study.

There have been found apoptotic changes in brain tissue samples from animals and humans after a traumatic brain injury (TBI). The protein cytokeratin 18 (CK-18), present in epithelial cells, is cleaved by the action of caspases during apoptosis, and the resulting fragments are released into the bloo...

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Bibliographic Details
Main Authors: Leonardo Lorente, María M Martín, Agustín F González-Rivero, Mónica Argueso, Luis Ramos, Jordi Solé-Violán, Juan J Cáceres, Alejandro Jiménez, Juan M Borreguero-León
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4379106?pdf=render

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http://europepmc.org/articles/PMC4379106?pdf=render

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