Embryo-scale epithelial buckling forms a propagating furrow that initiates gastrulation

Drosophila mesoderm invagination begins with the formation of a furrow. Here they show that a long-range mechanism, powered by actomyosin contraction between the embryo polar caps, works like a ‘cheese-cutter wire’ indenting the tissue surface and folding it into a propagating furrow.

Bibliographic Details
Main Authors: Julien Fierling, Alphy John, Barthélémy Delorme, Alexandre Torzynski, Guy B. Blanchard, Claire M. Lye, Anna Popkova, Grégoire Malandain, Bénédicte Sanson, Jocelyn Étienne, Philippe Marmottant, Catherine Quilliet, Matteo Rauzi
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30493-3