IL-1R and Inflammasomes Mediate Early Pulmonary Protective Mechanisms in Respiratory Brucella Abortus Infection

IL-1R and Inflammasomes Mediate Early Pulmonary Protective Mechanisms in Respiratory Brucella Abortus Infection

Brucella spp. infection is frequently acquired through contaminated aerosols. The role of interleukin-1 beta (IL-1β) in the early pulmonary response to respiratory Brucella infection is unknown. As shown here, IL-1β levels in lung homogenates and bronchoalveolar lavage fluid (BALF) of mice intratrac...

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Bibliographic Details
Main Authors: M. Soledad Hielpos, Andrea G. Fernández, Juliana Falivene, Iván M. Alonso Paiva, Florencia Muñoz González, Mariana C. Ferrero, Priscila C. Campos, Angelica T. Vieira, Sergio Costa Oliveira, Pablo C. Baldi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Brucella abortus
respiratory infection
innate immunity
IL-1β
inflammasomes
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00391/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2018.00391/full

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