Mass spectrometry analysis of gut tissue in acute SIV-infection in rhesus macaques identifies early proteome alterations preceding the interferon inflammatory response

Mass spectrometry analysis of gut tissue in acute SIV-infection in rhesus macaques identifies early proteome alterations preceding the interferon inflammatory response

Abstract HIV infection damages the gut mucosa leading to chronic immune activation, increased morbidities and mortality, and antiretroviral therapies, do not completely ameliorate mucosal dysfunction. Understanding early molecular changes in acute infection may identify new biomarkers underlying gut...

Full description

Bibliographic Details
Main Authors: A. R. Berard, T. Hensley-McBain, L. Noël-Romas, K. Birse, M. Abou, G. Westmacott, S. McCorrister, J. Smedley, Nichole R. Klatt, Adam D. Burgener
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-27112-y

Internet

https://doi.org/10.1038/s41598-022-27112-y

Similar Items