miR-16-5p Suppression Protects Human Cardiomyocytes against Endoplasmic Reticulum and Oxidative Stress-Induced Injury

miR-16-5p Suppression Protects Human Cardiomyocytes against Endoplasmic Reticulum and Oxidative Stress-Induced Injury

Oxidative stress, defined as the excess production of reactive oxygen species (ROS) relative to antioxidant defense, plays a significant role in the development of cardiovascular diseases. Endoplasmic reticulum (ER) stress has emerged as an important source of ROS and its modulation could be cardiop...

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Bibliographic Details
Main Authors: Rocío Toro, Alexandra Pérez-Serra, Alipio Mangas, Oscar Campuzano, Georgia Sarquella-Brugada, Maribel Quezada-Feijoo, Mónica Ramos, Martin Alcalá, Esther Carrera, Carlos García-Padilla, Diego Franco, Fernando Bonet
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
miR-16-5p
ischemic dilated cardiomyopathy
reactive oxygen species
endoplasmic reticulum stress
ATF6
Online Access:https://www.mdpi.com/1422-0067/23/3/1036

Internet

https://www.mdpi.com/1422-0067/23/3/1036

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