CD56-negative NK cells: Frequency in peripheral blood, expansion during HIV-1 infection, functional capacity, and KIR expression

CD56-negative NK cells: Frequency in peripheral blood, expansion during HIV-1 infection, functional capacity, and KIR expression

Human NK cells are usually defined as CD3-CD56+ lymphocytes. However, a CD56-CD16+ (CD56neg) lymphocyte population that displays NK-associated markers expands during chronic viral infections such as HIV-1 and HCV, and, to lesser extent, in herpesvirus infections. This CD56neg NK cell subset has been...

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Bibliographic Details
Main Authors: Alexander T. H. Cocker, Fuguo Liu, Zakia Djaoud, Lisbeth A. Guethlein, Peter Parham
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
NK cells
innate immunity
CD56neg
chronic infection
meta-analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.992723/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.992723/full

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