Bioengineering scalable and drug-responsive in vitro human multicellular non-alcoholic fatty liver disease microtissues encapsulated in the liver extracellular matrix-derived hydrogel

Bioengineering scalable and drug-responsive in vitro human multicellular non-alcoholic fatty liver disease microtissues encapsulated in the liver extracellular matrix-derived hydrogel

Non-alcoholic fatty liver disease (NAFLD) is a high-prevalence and progressive disorder. Due to lack of reliable in vitro models to recapitulate the consecutive phases, the exact pathogenesis mechanism of this disease and approved therapeutic medications have not been revealed yet. It has been prove...

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Bibliographic Details
Main Authors: Negar Asadollahi, Mohammad Amin Hajari, Mahmoud Alipour Choshali, Mohammad Ajoudanian, Seyed Ali Ziai, Massoud Vosough, Abbas Piryaei
Format: Article
Language:English
Published: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund 2024-03-01
Series:EXCLI Journal : Experimental and Clinical Sciences
Subjects:
non-alcoholic fatty liver disease
metabolic dysfunction-associated fatty liver disease
liver microtissue
bioengineering
drug screening
liraglutide
Online Access:https://www.excli.de/index.php/excli/article/view/6878

Internet

https://www.excli.de/index.php/excli/article/view/6878

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