The Bluetongue Disabled Infectious Single Animal (DISA) Vaccine Platform Based on Deletion NS3/NS3a Protein Is Safe and Protective in Cattle and Enables DIVA

The Bluetongue Disabled Infectious Single Animal (DISA) Vaccine Platform Based on Deletion NS3/NS3a Protein Is Safe and Protective in Cattle and Enables DIVA

The bluetongue virus (BTV) is transmitted by <i>Culicoides</i> biting midges and causes bluetongue (BT), an OIE-notifiable disease of ruminants. At least 29 BTV serotypes are described as determined by the outer shell proteins VP2 and VP5. Vaccination is the most effective control measur...

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Bibliographic Details
Main Authors: Piet A. van Rijn, Mieke A. Maris-Veldhuis, René G. P. van Gennip
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Viruses
Subjects:
bluetongue virus
vaccine platform
DISA principle
DIVA principle
NS3/NS3a protein
reverse genetics
Online Access:https://www.mdpi.com/1999-4915/13/5/857

Internet

https://www.mdpi.com/1999-4915/13/5/857

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