The potential neuroprotective effects of cannabinoids against paclitaxel-induced peripheral neuropathy: in vitro study on neurite outgrowth

Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) is a shared burden for 68.1% of oncological patients undergoing chemotherapy with Paclitaxel (PTX). The symptoms are intense and troublesome, patients reporting paresthesia, loss of sensation, and dysesthetic pain. While current medicat...

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Bibliographic Details
Main Authors: Ioana Creanga-Murariu, Leontina-Elena Filipiuc, Maria-Raluca Gogu, Mitica Ciorpac, Carmen Marinela Cumpat, Bogdan-Ionel Tamba, Teodora Alexa-Stratulat
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1395951/full