Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes

<p>Abstract</p> <p>Background</p> <p>In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one searches for differentially expressed genes, the small number of s...

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Bibliographic Details
Main Authors: Köstler Wolfgang J, Amir Amnon, Zeisel Amit, Domany Eytan
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/400