Baseline and post-treatment biomarkers of resistance to anti-PD-1 therapy in acral and mucosal melanoma: an observational study

Background Immunotherapies targeting programmed cell death-1 (PD-1) and its ligands have improved clinical outcomes for advanced melanoma. However, many tumors exhibit primary resistance or acquire secondary resistance after an initial positive response. The mechanisms of resistance are not well und...

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Bibliographic Details
Main Authors: Qing Zhao, Jeeyun Lee, Razvan Cristescu, Xiao Qiao Liu, Jennifer H. Yearley, Seung Tae Kim, Yuan Sun, Irene M. Shui, Tasmiah Choudhury, Andrea L. Webber, Clemens Krepler
Format: Article
Language:English
Published: BMJ Publishing Group 2022-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/7/e004879.full