Ventral hippocampal diacylglycerol lipase-alpha deletion decreases avoidance behaviors and alters excitation-inhibition balance

Ventral hippocampal diacylglycerol lipase-alpha deletion decreases avoidance behaviors and alters excitation-inhibition balance

The endogenous cannabinoid, 2-arachidonoylglycerol (2-AG), plays a key role in the regulation of anxiety- and stress-related behavioral phenotypes and may represent a novel target for the treatment of anxiety disorders. However, recent studies have suggested a more complex role for 2-AG signaling in...

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Bibliographic Details
Main Authors: Veronika Kondev, Rebecca Bluett, Mustafa Najeed, Luis E. Rosas-Vidal, Brad A. Grueter, Sachin Patel
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Neurobiology of Stress
Subjects:
Endocannabinoid
Stress
Ventral hippocampus
Fear conditioning
Anxiety
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289522000856

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http://www.sciencedirect.com/science/article/pii/S2352289522000856

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