On the clinical relevance of using complete high-resolution HLA typing for an accurate interpretation of posttransplant immune-mediated graft outcomes

On the clinical relevance of using complete high-resolution HLA typing for an accurate interpretation of posttransplant immune-mediated graft outcomes

Complete and high-resolution (HR) HLA typing improves the accurate assessment of donor–recipient compatibility and pre-transplant donor-specific antibodies (DSA). However, the value of this information to identify de novo immune-mediated graft events and its impact on outcomes has not been assessed....

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Bibliographic Details
Main Authors: Maria Meneghini, Anna Perona, Elena Crespo, Frederike Bemelman, Petra Reinke, Ondrej Viklicky, Magali Giral, Eduard Palou, Alba Torija, Laura Donadeu, Edoardo Melilli, Jose Zuñiga, Anett Sefrin, Nils Lachmann, Liu Hu, Petra Hruba, Cécile Guillot-Gueguen, Sophie Brouard, Josep Grinyo, Oriol Bestard
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
HLA typing
donor-specific antibodies
allograft rejection
precision medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.924825/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.924825/full

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