Dietary long-chain fatty acids promote colitis by regulating palmitoylation of STAT3 through CD36-mediated endocytosis

Dietary long-chain fatty acids promote colitis by regulating palmitoylation of STAT3 through CD36-mediated endocytosis

Abstract The Western diet, characterized by its high content of long-chain fatty acids (LCFAs), is widely recognized as a significant triggering factor for inflammatory bowel disease (IBD). While the link between a high-fat diet and colitis has been observed, the specific effects and mechanisms rema...

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Bibliographic Details
Main Authors: Yuping Wei, Jinting Li, Jiao Li, Chuan Liu, Xingzhou Guo, Zhengru Liu, Luyun Zhang, Shenglan Bao, Xiaohan Wu, Wenhao Su, Xiaoli Wang, Jixiang Zhang, Weiguo Dong
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06456-5

Internet

https://doi.org/10.1038/s41419-024-06456-5

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