KEAP1 promotes anti-tumor immunity by inhibiting PD-L1 expression in NSCLC

KEAP1 promotes anti-tumor immunity by inhibiting PD-L1 expression in NSCLC

Abstract Immunotherapy has become a prominent first-line cancer treatment strategy. In non-small cell lung cancer (NSCLC), the expression of PD-L1 induces an immuno-suppressive effect to protect cancer cells from immune elimination, which designates PD-L1 as an important target for immunotherapy. Ho...

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Bibliographic Details
Main Authors: Jinghan Li, Daiwang Shi, Siyi Li, Xiang Shi, Yu Liu, Yi Zhang, Gebang Wang, Chenlei Zhang, Tian Xia, Hai-long Piao, Hong-Xu Liu
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06563-3

Internet

https://doi.org/10.1038/s41419-024-06563-3

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