Dicarbonyl Stress at the Crossroads of Healthy and Unhealthy Aging

Dicarbonyl Stress at the Crossroads of Healthy and Unhealthy Aging

Dicarbonyl stress occurs when dicarbonyl metabolites (i.e., methylglyoxal, glyoxal and 3-deoxyglucosone) accumulate as a consequence of their increased production and/or decreased detoxification. This toxic condition has been associated with metabolic and age-related diseases, both of which are char...

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Bibliographic Details
Main Authors: Cecilia Nigro, Alessia Leone, Francesca Fiory, Immacolata Prevenzano, Antonella Nicolò, Paola Mirra, Francesco Beguinot, Claudia Miele
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
aging
diabetes mellitus
dicarbonyl stress
glycation
glyoxalase system
hormesis
methylglyoxal
neurodegeneration
obesity
vascular complications
Online Access:https://www.mdpi.com/2073-4409/8/7/749

Internet

https://www.mdpi.com/2073-4409/8/7/749

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