Highly Charged Ru(II) Polypyridyl Complexes as Photosensitizer Agents in Photodynamic Therapy of Epithelial Ovarian Cancer Cells

Highly Charged Ru(II) Polypyridyl Complexes as Photosensitizer Agents in Photodynamic Therapy of Epithelial Ovarian Cancer Cells

Ovarian cancer recurrence is frequent and associated with chemoresistance, leading to extremely poor prognosis. Herein, we explored the potential anti-cancer effect of a series of highly charged Ru(II)-polypyridyl complexes as photosensitizers in photodynamic therapy (PDT), which were able to effici...

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Bibliographic Details
Main Authors: Luca Conti, Gina Elena Giacomazzo, Barbara Valtancoli, Mauro Perfetti, Alberto Privitera, Claudia Giorgi, Patrick Severin Sfragano, Ilaria Palchetti, Sara Pecchioli, Paola Bruni, Francesca Cencetti
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
drug discovery
coordination complexes
phototoxicity
reactive oxygen species
Online Access:https://www.mdpi.com/1422-0067/23/21/13302

Internet

https://www.mdpi.com/1422-0067/23/21/13302

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