Pharmaceutical and Safety Profile Evaluation of Novel Selenocompounds with Noteworthy Anticancer Activity

Pharmaceutical and Safety Profile Evaluation of Novel Selenocompounds with Noteworthy Anticancer Activity

Prior studies have reported the potent and selective cytotoxic, pro-apoptotic, and chemopreventive activities of a cyclic selenoanhydride and of a series of selenoesters. Some of these selenium derivatives demonstrated multidrug resistance (MDR)-reversing activity in different resistant cancer cell...

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Bibliographic Details
Main Authors: Małgorzata Anna Marć, Enrique Domínguez-Álvarez, Gniewomir Latacz, Agata Doroz-Płonka, Carmen Sanmartín, Gabriella Spengler, Jadwiga Handzlik
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceutics
Subjects:
selenoesters
ADMET
anticancer activity
pharmaceutical profile
PAMPA
metabolic stability
Online Access:https://www.mdpi.com/1999-4923/14/2/367

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https://www.mdpi.com/1999-4923/14/2/367

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