Aspirin Inhibits IKK-β-mediated Prostate Cancer Cell Invasion by Targeting Matrix Metalloproteinase-9 and Urokinase-Type Plasminogen Activator

Aspirin Inhibits IKK-β-mediated Prostate Cancer Cell Invasion by Targeting Matrix Metalloproteinase-9 and Urokinase-Type Plasminogen Activator

Background/Aims: Aspirin has been demonstrated to possess potent chemopreventive and anticancer effects on prostate cancer. However, the more detailed molecular mechanisms of aspirin to suppress prostate cancer cell invasion have not been clearly elucidated. Methods: Transwell assays were performed...

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Hlavní autoři: Chongjun Shi, Nini Zhang, Yang Feng, Jiewei Cao, Xuyi Chen, Bin Liu
Médium: Článek
Jazyk:English
Vydáno: Cell Physiol Biochem Press GmbH & Co KG 2017-03-01
Edice:Cellular Physiology and Biochemistry
Témata:
Invasion
Matrix metalloproteinase
Nuclear factor-kappa B
Prostate cancer
Urokinase-type plasminogen activator
On-line přístup:http://www.karger.com/Article/FullText/464434

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