Distinct clinical and biological implications of CUX1 in myeloid neoplasms

Distinct clinical and biological implications of CUX1 in myeloid neoplasms

Abstract: Somatic mutations of the CUT-like homeobox 1 (CUX1) gene (CUX1MT) can be found in myeloid neoplasms (MNs), in particular, in myelodysplastic syndromes (MDSs). The CUX1 locus is also deleted in 3 of 4 MN cases with −7/del(7q). A cohort of 1480 MN patients was used to characterize clinical f...

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Bibliographic Details
Main Authors: Mai Aly, Zubaidah M. Ramdzan, Yasunobu Nagata, Suresh K. Balasubramanian, Naoko Hosono, Hideki Makishima, Valeria Visconte, Teodora Kuzmanovic, Vera Adema, Aziz Nazha, Bartlomiej P. Przychodzen, Cassandra M. Kerr, Mikkael A. Sekeres, Mohamed E. Abazeed, Alain Nepveu, Jaroslaw P. Maciejewski
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920306509

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http://www.sciencedirect.com/science/article/pii/S2473952920306509

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