The Modulation of NMDA and AMPA/Kainate Receptors by Tocotrienol-Rich Fraction and Α-Tocopherol in Glutamate-Induced Injury of Primary Astrocytes

Astrocytes are known as structural and supporting cells in the central nervous system (CNS). Glutamate, as a main excitatory amino acid neurotransmitter in the mammalian central nervous system, can be excitotoxic, playing a key role in many chronic neurodegenerative diseases. The aim of the current...

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Bibliographic Details
Main Authors: Zahra Abedi, Huzwah Khaza’ai, Sharmili Vidyadaran, Mohd Sokhini Abd Mutalib
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/5/4/68