Cutaneous wound healing promoted by topical administration of heat-killed Lactobacillus plantarum KB131 and possible contribution of CARD9-mediated signaling

Abstract Optimal conditions for wound healing require a smooth transition from the early stage of inflammation to proliferation, and during this time alternatively activated (M2) macrophages play a central role. Recently, heat-killed lactic acid bacteria (LAB), such as Lactobacillus plantarum (L. pl...

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Bibliographic Details
Main Authors: Shinyo Ishi, Emi Kanno, Hiromasa Tanno, Shiho Kurosaka, Miki Shoji, Toshiro Imai, Kenji Yamaguchi, Kanna Kotsugai, Momoko Niiyama, Haruko Kurachi, Fuko Makabe, Takumi Watanabe, Ko Sato, Keiko Ishii, Hiromitsu Hara, Yoshimichi Imai, Kazuyoshi Kawakami
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42919-z