A novel delivery nanobiotechnology: engineered miR-181b exosomes improved osteointegration by regulating macrophage polarization

A novel delivery nanobiotechnology: engineered miR-181b exosomes improved osteointegration by regulating macrophage polarization

Abstract Background Many patients suffer from implant loosening after the implantation of titanium alloy caused by immune response to the foreign bodies and this could inhibit the following osteogenesis, which could possibly give rise to aseptic loosening and poor osteointegration while there is cur...

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Bibliographic Details
Main Authors: Wei Liu, Muyu Yu, Feng Chen, Longqing Wang, Cheng Ye, Qing Chen, Qi Zhu, Dong Xie, Mingzhe Shao, Lili Yang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Nanobiotechnology
Subjects:
Engineered
Exosome
Macrophage polarization
MiR-181b
Osteointegration
Inflammation
Online Access:https://doi.org/10.1186/s12951-021-01015-y

Internet

https://doi.org/10.1186/s12951-021-01015-y

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