Mutation screen in the GWAS derived obesity gene <it>SH2B1</it> including functional analyses of detected variants

Mutation screen in the GWAS derived obesity gene <it>SH2B1</it> including functional analyses of detected variants

<p>Abstract</p> <p>Background</p> <p>The <it>SH2B1</it> gene (Src-homology 2B adaptor protein 1 gene) is a solid candidate gene for obesity. Large scale GWAS studies depicted markers in the vicinity of the gene; animal models suggest a potential relevance fo...

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Bibliographic Details
Main Authors: Volckmar Anna-Lena, Bolze Florian, Jarick Ivonne, Knoll Nadja, Scherag André, Reinehr Thomas, Illig Thomas, Grallert Harald, Wichmann Heinz-Erich, Wiegand Susanna, Biebermann Heike, Krude Heiko, Fischer-Posovszky Pamela, Rief Winfried, Wabitsch Martin, Klingenspor Martin, Hebebrand Johannes, Hinney Anke
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Medical Genomics
Subjects:
SH2B1
Obesity
BMI
rs7498665
Mutation screen
Online Access:http://www.biomedcentral.com/1755-8794/5/65

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http://www.biomedcentral.com/1755-8794/5/65

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