Response of Fibroblasts from Menkes’ and Wilson’s Copper Metabolism-Related Disorders to Ionizing Radiation: Influence of the Nucleo-Shuttling of the ATM Protein Kinase

Menkes’ disease (MD) and Wilson’s disease (WD) are two major copper (Cu) metabolism-related disorders caused by mutations of the <i>ATP7A</i> and <i>ATP7B</i> ATPase gene, respectively. While Cu is involved in DNA strand breaks signaling and repair, the response of cells from...

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Bibliographic Details
Main Authors: Laura El Nachef, Joëlle Al-Choboq, Michel Bourguignon, Nicolas Foray
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/13/12/1746