Catalase-Like Antioxidant Activity is Unaltered in Hypochlorous Acid Oxidized Horse Heart Myoglobin

Catalase-Like Antioxidant Activity is Unaltered in Hypochlorous Acid Oxidized Horse Heart Myoglobin

Activated neutrophils release myeloperoxidase that produces the potent oxidant hypochlorous acid (HOCl). Exposure of the oxygen transport protein horse heart myoglobin (hhMb) to HOCl inhibits Iron III (Fe(III))-heme reduction by cytochrome <i>b</i>5 to oxygen-binding Iron II (Fe(II))Mb....

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Bibliographic Details
Main Authors: Gulfam Ahmad, Belal Chami, Mary El Kazzi, Xiaosuo Wang, Maria Tereza S. Moreira, Natasha Hamilton, Aung Min Maw, Thomas W. Hambly, Paul K. Witting
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Antioxidants
Subjects:
myoglobin
hypochlorous acid
protein oxidation
haem-iron reduction
MetMb reductase
catalase-like antioxidant activity
Online Access:https://www.mdpi.com/2076-3921/8/9/414

Internet

https://www.mdpi.com/2076-3921/8/9/414

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