Time-varying and tissue-dependent effects of adiposity on leptin levels: A Mendelian randomization study

Background: Findings from Mendelian randomization (MR) studies are conventionally interpreted as lifelong effects, which typically do not provide insight into the molecular mechanisms underlying the effect of an exposure on an outcome. In this study, we apply two recently developed MR approaches (kn...

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Bibliographic Details
Main Authors: Tom G Richardson, Genevieve M Leyden, George Davey Smith
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/84646