Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics

Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics

Abstract Elucidating functions of commensal microbial genes in the mammalian gut is challenging because many commensals are recalcitrant to laboratory cultivation and genetic manipulation. We present Temporal FUnctional Metagenomics sequencing (TFUMseq), a platform to functionally mine bacterial gen...

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Bibliographic Details
Main Authors: Stephanie J Yaung, Luxue Deng, Ning Li, Jonathan L Braff, George M Church, Lynn Bry, Harris H Wang, Georg K Gerber
Format: Article
Language:English
Published: Springer Nature 2015-03-01
Series:Molecular Systems Biology
Subjects:
commensal fitness
functional metagenomics
microbiota
next‐generation sequencing
synthetic biology
Online Access:https://doi.org/10.15252/msb.20145866

Internet

https://doi.org/10.15252/msb.20145866

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