Linking Chromosomal Silencing With Xist Expression From Autosomal Integrated Transgenes
Xist is the master regulator of X-Chromosome Inactivation (XCI), the mammalian dosage compensation mechanism that silences one of the two X chromosomes in a female cell. XCI is established during early embryonic development. Xist transgene (Tg) integrated into an autosome can induce transcriptional...
| Auteurs principaux: | , , , , , , , |
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| Format: | Article |
| Langue: | English |
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Frontiers Media S.A.
2021-06-01
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| Collection: | Frontiers in Cell and Developmental Biology |
| Sujets: | |
| Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fcell.2021.693154/full |