Comparison of Two Dosing Regimens of Miltefosine, Both in Combination With Allopurinol, on Clinical and Parasitological Findings of Dogs With Leishmaniosis: A Pilot Study

Comparison of Two Dosing Regimens of Miltefosine, Both in Combination With Allopurinol, on Clinical and Parasitological Findings of Dogs With Leishmaniosis: A Pilot Study

Miltefosine (MIL)–allopurinol combination therapy administered at standard dosage is effective to treat canine leishmaniosis, nevertheless for some dogs the digestive tolerance of MIL is not acceptable. This study evaluates an alternative therapeutic protocol by using a modified dosage of MIL to inc...

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Bibliographic Details
Main Authors: Fabrizio Iarussi, Paola Paradies, Valentina Foglia Manzillo, Manuela Gizzarelli, Mariano Francesco Caratozzolo, Christelle Navarro, Beatrice Greco, Giuseppe Tommaso Roberto Rubino, Gaetano Oliva, Mariateresa Sasanelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Veterinary Science
Subjects:
canine leishmaniosis
modified miltefosine dosage
treatment efficacy
digestive tolerance
combination therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2020.577395/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2020.577395/full

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