RBP7 functions as a tumor suppressor in HR + breast cancer by inhibiting the AKT/SREBP1 pathway and reducing fatty acid

RBP7 functions as a tumor suppressor in HR + breast cancer by inhibiting the AKT/SREBP1 pathway and reducing fatty acid

Abstract Background Increasing evidence proves that RBP7 plays a significant role in breast cancer (BC). The present study was aimed to investigate the mechanism of RBP7. Methods Western Blotting and qRT-PCR were performed for evaluating the expression levels. CCK8, colony forming, xenograft mouse m...

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Bibliographic Details
Main Authors: Yue Yu, Zhihua Xu, Hao Zhou, Ruyan Xu, Jia Xu, Wenjun Liu, Yuxin Wu, Yue Qiu, Guangbo Zhang, Xue Huang, Yan Chen
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Cancer Cell International
Subjects:
Breast cancer
RBP7
Prognosis
Fatty acid metabolism
Nomogram
Online Access:https://doi.org/10.1186/s12935-024-03299-0

Internet

https://doi.org/10.1186/s12935-024-03299-0

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