The In Silico Prediction of Hotspot Residues that Contribute to the Structural Stability of Subunit Interfaces of a Picornavirus Capsid

The assembly of picornavirus capsids proceeds through the stepwise oligomerization of capsid protein subunits and depends on interactions between critical residues known as hotspots. Few studies have described the identification of hotspot residues at the protein subunit interfaces of the picornavir...

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Bibliographic Details
Main Authors: Nicole Upfold, Caroline Ross, Özlem Tastan Bishop, Caroline Knox
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/4/387