Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid

Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid

Background: Blood-cerebrospinal fluid (CSF) barrier transporters affect the influx and efflux of drugs. The antiretrovirals tenofovir and emtricitabine may be substrates of blood-brain barrier (BBB) and blood-CSF barrier transporters, but data are limited regarding the pharmacogenetics and pharmacok...

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Bibliographic Details
Main Authors: Eric H. Decloedt, Phumla Z. Sinxadi, Lubbe Wiesner, John A. Joska, David W. Haas, Gary Maartens
Format: Article
Language:English
Published: AOSIS 2021-04-01
Series:Southern African Journal of HIV Medicine
Subjects:
pharmacokinetics
pharmacogenetics
tenofovir
emtricitabine
cerebrospinal fluid
Online Access:https://sajhivmed.org.za/index.php/hivmed/article/view/1206

Internet

https://sajhivmed.org.za/index.php/hivmed/article/view/1206

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