FHL2 promotes the aggressiveness of lung adenocarcinoma by inhibiting autophagy via activation of the PI3K/AKT/mTOR pathway

FHL2 promotes the aggressiveness of lung adenocarcinoma by inhibiting autophagy via activation of the PI3K/AKT/mTOR pathway

Abstract Background Increasing evidence indicates that four and a half LIM domains 2 (FHL2) plays a crucial role in the progression of various cancers. However, the biological functions and molecular mechanism of FHL2 in lung adenocarcinoma (LUAD) remain unclear. Methods We evaluated the prognostic...

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Bibliographic Details
Main Authors: Shuaishuai Wang, Baomo Liu, Yan Su, Nian Wang, Peixin Dong, Xiongye Xu, Lixia Huang, Shaoli Li, Jincui Gu, Yanli Qiu, Jiating Deng, Ziying Lin, Yanbin Zhou
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Thoracic Cancer
Subjects:
autophagy
FHL2
lung adenocarcinoma
PI3K/AKT/mTOR pathway
Online Access:https://doi.org/10.1111/1759-7714.15234

Internet

https://doi.org/10.1111/1759-7714.15234

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