FHL2 promotes the aggressiveness of lung adenocarcinoma by inhibiting autophagy via activation of the PI3K/AKT/mTOR pathway

FHL2 promotes the aggressiveness of lung adenocarcinoma by inhibiting autophagy via activation of the PI3K/AKT/mTOR pathway

Abstract Background Increasing evidence indicates that four and a half LIM domains 2 (FHL2) plays a crucial role in the progression of various cancers. However, the biological functions and molecular mechanism of FHL2 in lung adenocarcinoma (LUAD) remain unclear. Methods We evaluated the prognostic...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Shuaishuai Wang, Baomo Liu, Yan Su, Nian Wang, Peixin Dong, Xiongye Xu, Lixia Huang, Shaoli Li, Jincui Gu, Yanli Qiu, Jiating Deng, Ziying Lin, Yanbin Zhou
Format: Artykuł
Język:English
Wydane: Wiley 2024-03-01
Seria:Thoracic Cancer
Hasła przedmiotowe:
autophagy
FHL2
lung adenocarcinoma
PI3K/AKT/mTOR pathway
Dostęp online:https://doi.org/10.1111/1759-7714.15234

Internet

https://doi.org/10.1111/1759-7714.15234

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