Stochastic Ratcheting on a Funneled Energy Landscape Is Necessary for Highly Efficient Contractility of Actomyosin Force Dipoles

Current understanding of how contractility emerges in disordered actomyosin networks of nonmuscle cells is still largely based on the intuition derived from earlier works on muscle contractility. In addition, in disordered networks, passive cross-linkers have been hypothesized to percolate force cha...

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Bibliographic Details
Main Authors: James E. Komianos, Garegin A. Papoian
Format: Article
Language:English
Published: American Physical Society 2018-04-01
Series:Physical Review X
Online Access:http://doi.org/10.1103/PhysRevX.8.021006