Curcumin protects against manganese-induced neurotoxicity in rat by regulating oxidative stress-related gene expression via H3K27 acetylation

Curcumin protects against manganese-induced neurotoxicity in rat by regulating oxidative stress-related gene expression via H3K27 acetylation

Long-term manganese exposure causes a neurodegenerative disorder referred to as manganese poisoning, but the mechanism remains unclear and no specific treatment is available. Oxidative stress is widely recognised as one of the main causes of manganese-induced neurotoxicity. In recent years, the role...

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Bibliographic Details
Main Authors: Yue Yang, Ying Liu, An-Liu Zhang, Shun-Fang Tang, Qian Ming, Chun-Yan Ao, Yan Liu, Chang-Zhe Li, Chun Yu, Hua Zhao, Li Chen, Jun Li
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Curcumin
Manganese
H3K18 acetylation
H3K27 acetylation
Oxidative stress
Neurodegenerative disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322003098

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http://www.sciencedirect.com/science/article/pii/S0147651322003098

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