Early-life undernutrition induces enhancer RNA remodeling in mice liver

Early-life undernutrition induces enhancer RNA remodeling in mice liver

Abstract Background Maternal protein restriction diet (PRD) increases the risk of metabolic dysfunction in adulthood, the mechanisms during the early life of offspring are still poorly understood. Apart from genetic factors, epigenetic mechanisms are crucial to offer phenotypic plasticity in respons...

Full description

Bibliographic Details
Main Authors: Yinyu Wang, Yiting Mao, Yiran Zhao, Xianfu Yi, Guolian Ding, Chuanjin Yu, Jianzhong Sheng, Xinmei Liu, Yicong Meng, Hefeng Huang
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Epigenetics & Chromatin
Subjects:
Early-life undernutrition
Global run-on sequencing
Nascent RNA
Enhancer
Metabolism
Online Access:https://doi.org/10.1186/s13072-021-00392-w

Internet

https://doi.org/10.1186/s13072-021-00392-w

Similar Items