CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice

CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice

Gene expression analyses suggest that more than 1000–2000 genes are expressed predominantly in mouse and human testes. Although functional analyses of hundreds of these genes have been performed, there are still many testis-enriched genes whose functions remain unexplored. Analyzing gene function us...

Full description

Bibliographic Details
Main Authors: Yuki Oyama, Haruhiko Miyata, Keisuke Shimada, Yoshitaka Fujihara, Keizo Tokuhiro, Thomas X Garcia, Martin M Matzuk, Masahito Ikawa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Asian Journal of Andrology
Subjects:
crispr/cas9; knockout mice; male infertility; spermatozoa; testis
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=3;spage=266;epage=272;aulast=Oyama

Internet

http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=3;spage=266;epage=272;aulast=Oyama

Similar Items