TGF-β controls development of TCRγδ+CD8αα+ intestinal intraepithelial lymphocytes
Abstract γδ intestinal intraepithelial lymphocytes (IELs) constitute the majority of IELs with unique CD8αα+ homodimers that are distinct from γδT cells in other tissues. However, it remains largely unclear how those cells develop. Here we show that transforming growth factor beta (TGF-β) signaling...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2023-05-01
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| Series: | Cell Discovery |
| Online Access: | https://doi.org/10.1038/s41421-023-00542-2 |