Integration of a single-step genome-wide association study with a multi-tissue transcriptome analysis provides novel insights into the genetic basis of wool and weight traits in sheep

Abstract Background Genetic improvement of wool and growth traits is a major goal in the sheep industry, but their underlying genetic architecture remains elusive. To improve our understanding of these mechanisms, we conducted a weighted single-step genome-wide association study (WssGWAS) and then i...

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Bibliographic Details
Main Authors: Bingru Zhao, Hanpeng Luo, Xixia Huang, Chen Wei, Jiang Di, Yuezhen Tian, Xuefeng Fu, Bingjie Li, George E. Liu, Lingzhao Fang, Shengli Zhang, Kechuan Tian
Format: Article
Language:deu
Published: BMC 2021-06-01
Series:Genetics Selection Evolution
Online Access:https://doi.org/10.1186/s12711-021-00649-8