MicroRNAs in adult high-grade gliomas: Mechanisms of chemotherapeutic resistance and their clinical relevance

Notorious for its high mortality rate, the current standard treatment for high-grade gliomas remains a challenge. This is largely due to the complex heterogeneity of the tumour coupled with dysregulated molecular mechanisms leading to the development of drug resistance. In recent years, microRNAs (m...

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Bibliographic Details
Main Authors: Yugendran Jegathesan, Pashaun Paveen Stephen, Isra Saif Eldin Eisa Sati, Prakrithi Narayanan, Mastura Monif, Muhamad Noor Alfarizal Kamarudin
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224001586