Causal association between major depressive disorder and coronary heart disease: a two-sample bidirectional mendelian randomization study

Causal association between major depressive disorder and coronary heart disease: a two-sample bidirectional mendelian randomization study

Abstract Background Major depressive disorder (MDD) is a highly heterogeneous mental illness and a major public health problem worldwide. A large number of observational studies have demonstrated a clear association between MDD and coronary heart disease (CHD), and some studies have even suggested t...

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Bibliographic Details
Main Authors: Qianjie Xu, Chen Chen, Ruijia You, Linghao Ni, Siyu Chen, Bin Peng
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Medical Genomics
Subjects:
Major depressive disorder
Coronary heart disease
Causal inference
Bidirectional causality
Mendelian Randomization
Online Access:https://doi.org/10.1186/s12920-023-01625-5

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