Molecular recognition in complexes of TRF proteins with telomeric DNA.

Telomeres are specialized nucleoprotein assemblies that protect the ends of linear chromosomes. In humans and many other species, telomeres consist of tandem TTAGGG repeats bound by a protein complex known as shelterin that remodels telomeric DNA into a protective loop structure and regulates telome...

Full description

Bibliographic Details
Main Authors: Miłosz Wieczór, Adrian Tobiszewski, Paweł Wityk, Bartłomiej Tomiczek, Jacek Czub
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3935891?pdf=render