A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins

A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins

How the cuticles of the roughly 4.5 million species of ecdysozoan animals are constructed is not well understood. Here, we systematically mine gene expression datasets to uncover the spatiotemporal blueprint for how the chitin-based pharyngeal cuticle of the nematode Caenorhabditis elegans is built....

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Bibliographic Details
Main Authors: Muntasir Kamal, Levon Tokmakjian, Jessica Knox, Peter Mastrangelo, Jingxiu Ji, Hao Cai, Jakub W Wojciechowski, Michael P Hughes, Kristóf Takács, Xiaoquan Chu, Jianfeng Pei, Vince Grolmusz, Malgorzata Kotulska, Julie Deborah Forman-Kay, Peter J Roy
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
cuticle
intrinsically disordered proteins
molting
systems analyses
phase separation
novel gene families
Online Access:https://elifesciences.org/articles/79396

Internet

https://elifesciences.org/articles/79396

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