Expression of constitutively active erythropoietin receptor in pyramidal neurons of cortex and hippocampus boosts higher cognitive functions in mice

<p>Abstract</p> <p>Background</p> <p>Erythropoietin (EPO) and its receptor (EPOR) are expressed in the developing brain and their transcription is upregulated in adult neurons and glia upon injury or neurodegeneration. We have shown neuroprotective effects and improved...

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Bibliographic Details
Main Authors: Hassouna Imam, Wojcik Sonja M, Müller Michael, Agarwal Amit, El-Kordi Ahmed, Sargin Derya, Sperling Swetlana, Nave Klaus-Armin, Ehrenreich Hannelore
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/9/27