Re-examining the factor structure of the Insomnia Severity Index (ISI) and defining the meaningful within-individual change (MWIC) for subjects with insomnia disorder in two phase III clinical trials of the efficacy of lemborexant

Re-examining the factor structure of the Insomnia Severity Index (ISI) and defining the meaningful within-individual change (MWIC) for subjects with insomnia disorder in two phase III clinical trials of the efficacy of lemborexant

Abstract Background The Insomnia Severity Index (ISI) is a widely used measure of insomnia severity. Various ISI research findings suggest different factor solutions and meaningful within-individual change (MWIC) to detect treatment response in patients with insomnia. This study examined an ISI fact...

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Bibliographic Details
Main Authors: William R. Lenderking, Yulia Savva, Mark J. Atkinson, Renee Campbell, Isabelle Chabot, Margaret Moline, Genevieve Meier, Charles M. Morin
Format: Article
Language:English
Published: SpringerOpen 2024-06-01
Series:Journal of Patient-Reported Outcomes
Subjects:
Clinically meaningful change
Confirmatory factor analysis
Insomnia
Insomnia Severity Index
Lemborexant
Meaningful within-individual change
Online Access:https://doi.org/10.1186/s41687-024-00744-6

Internet

https://doi.org/10.1186/s41687-024-00744-6

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