Investigating the shared genetic basis of inflammatory bowel disease and systemic lupus erythematosus using genetic overlap analysis

Investigating the shared genetic basis of inflammatory bowel disease and systemic lupus erythematosus using genetic overlap analysis

Abstract Background Inflammatory bowel disease (IBD) and systemic lupus erythematosus (SLE) are autoimmune diseases that often coexist clinically. This phenomenon might be due to shared genetic components. Methods Genome-wide association study (GWAS) data for IBD and SLE were analyzed to determine b...

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Bibliographic Details
Main Authors: Weichao Yuan, Qinghua Luo, Na Wu
Format: Article
Language:English
Published: BMC 2024-09-01
Series:BMC Genomics
Subjects:
Genetic overlap
Genetic structure
Genetic risk loci
Systemic lupus erythematosus
Inflammatory bowel disease
Online Access:https://doi.org/10.1186/s12864-024-10787-0

Internet

https://doi.org/10.1186/s12864-024-10787-0

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