Microgliosis and neuronal proteinopathy in brain persist beyond viral clearance in SARS-CoV-2 hamster model

Microgliosis and neuronal proteinopathy in brain persist beyond viral clearance in SARS-CoV-2 hamster model

Summary: Background: Neurological symptoms such as cognitive decline and depression contribute substantially to post-COVID-19 syndrome, defined as lasting symptoms several weeks after initial SARS-CoV-2 infection. The pathogenesis is still elusive, which hampers appropriate treatment. Neuroinflamma...

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Bibliographic Details
Main Authors: Christopher Käufer, Cara S. Schreiber, Anna-Sophia Hartke, Ivo Denden, Stephanie Stanelle-Bertram, Sebastian Beck, Nancy Mounogou Kouassi, Georg Beythien, Kathrin Becker, Tom Schreiner, Berfin Schaumburg, Andreas Beineke, Wolfgang Baumgärtner, Gülsah Gabriel, Franziska Richter
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:EBioMedicine
Subjects:
Alpha-synuclein
Tau
Neuroinfection
Neurodegenerative disease
Animal model
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422001839

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http://www.sciencedirect.com/science/article/pii/S2352396422001839

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