Mutational Landscape of CEBPA in Mexican Pediatric Acute Myeloid Leukemia Patients: Prognostic Implications

Mutational Landscape of CEBPA in Mexican Pediatric Acute Myeloid Leukemia Patients: Prognostic Implications

BackgroundIn Mexico, the incidence of acute myeloid leukemia (AML) has increased in the last few years. Mortality is higher than in developed countries, even though the same chemotherapy protocols are used. CCAAT Enhancer Binding Protein Alpha (CEBPA) mutations are recurrent in AML, influence progno...

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Main Authors: Carolina Molina Garay, Karol Carrillo Sánchez, Luis Leonardo Flores Lagunes, Marco Jiménez Olivares, Anallely Muñoz Rivas, Beatríz Eugenia Villegas Torres, Hilario Flores Aguilar, Juan Carlos Núñez Enríquez, Elva Jiménez Hernández, Vilma Carolina Bekker Méndez, José Refugio Torres Nava, Janet Flores Lujano, Jorge Alfonso Martín Trejo, Minerva Mata Rocha, Aurora Medina Sansón, Laura Eugenia Espinoza Hernández, José Gabriel Peñaloza Gonzalez, Rosa Martha Espinosa Elizondo, Luz Victoria Flores Villegas, Raquel Amador Sanchez, María Luisa Pérez Saldívar, Omar Alejandro Sepúlveda Robles, Haydeé Rosas Vargas, Silvia Jiménez Morales, Patricia Galindo Delgado, Juan Manuel Mejía Aranguré, Carmen Alaez Verson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pediatrics
Subjects:
CEBPA
pediatric
Mexican
AML
survival
risk-stratification
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2022.899742/full

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https://www.frontiersin.org/articles/10.3389/fped.2022.899742/full

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